KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2A
All Species:
16.06
Human Site:
S1579
Identified Species:
35.33
UniProt:
P24928
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24928
NP_000928.1
1970
217176
S1579
P
G
S
P
G
P
S
S
P
Y
I
P
S
P
G
Chimpanzee
Pan troglodytes
XP_511300
1913
211215
S1579
P
G
S
P
G
P
S
S
P
Y
I
P
S
P
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_858599
1896
209574
P1580
S
P
G
G
A
M
S
P
S
Y
S
P
T
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P08775
1970
217158
S1579
P
G
S
P
G
P
S
S
P
Y
I
P
S
P
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
D1092
I
T
A
Q
L
D
K
D
D
D
P
D
F
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_682682
1972
217631
S1576
P
G
S
P
G
P
A
S
P
Y
I
P
S
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04052
1887
209150
A1571
S
M
S
P
Y
F
P
A
S
P
S
V
S
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P16356
1852
203961
S1541
G
N
T
D
G
G
A
S
P
F
N
E
G
G
W
Sea Urchin
Strong. purpuratus
XP_001176260
1921
212544
Y1579
G
S
P
A
N
S
P
Y
I
P
S
P
A
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P18616
1840
204671
F1537
P
Y
V
G
G
M
A
F
S
P
S
S
S
P
G
Baker's Yeast
Sacchar. cerevisiae
P04050
1733
191593
I1429
R
G
V
S
E
N
V
I
L
G
Q
M
A
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
N.A.
95.9
N.A.
99.9
N.A.
N.A.
N.A.
26.2
N.A.
94.9
N.A.
71.1
N.A.
67.4
77.6
Protein Similarity:
100
96.8
N.A.
96
N.A.
99.9
N.A.
N.A.
N.A.
40.8
N.A.
97.8
N.A.
84.1
N.A.
81
87.2
P-Site Identity:
100
100
N.A.
20
N.A.
100
N.A.
N.A.
N.A.
0
N.A.
93.3
N.A.
26.6
N.A.
20
6.6
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
N.A.
N.A.
N.A.
6.6
N.A.
100
N.A.
33.3
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.4
50.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.9
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
0
28
10
0
0
0
0
19
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
10
10
10
0
10
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
10
0
0
10
0
0
% F
% Gly:
19
46
10
19
55
10
0
0
0
10
0
0
10
19
46
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
10
0
37
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
19
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
0
10
10
0
0
0
0
10
0
0
0
0
% N
% Pro:
46
10
10
46
0
37
19
10
46
28
10
55
0
64
19
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
19
10
46
10
0
10
37
46
28
0
37
10
55
10
10
% S
% Thr:
0
10
10
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
19
0
0
0
10
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
10
0
0
10
0
0
10
0
46
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _